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Journal article

Identifying and quantifying the role of inflammation in pain reduction for patients with psoriatic arthritis treated with tofacitinib: a mediation analysis

Abstract:

Introduction: Pain is a multidimensional factor and core domain of psoriatic arthritis (PsA). This analysis aimed to quantify the role of potential inflammation-associated outcomes on pain reduction in patients with PsA receiving tofacitinib, using mediation modeling.

Methods: Pooled data were from two phase 3 studies (OPAL Broaden and OPAL Beyond) of patients with active PsA treated with tofacitinib 5 mg twice daily or placebo. Media...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1007/s40744-022-00482-5

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Publisher:
Springer
Journal:
Rheumatology and Therapy More from this journal
Volume:
9
Pages:
1451-1464
Publication date:
2022-09-08
Acceptance date:
2022-08-01
DOI:
EISSN:
2198-6584
ISSN:
2198-6576
Language:
English
Keywords:
Pubs id:
1282148
Local pid:
pubs:1282148
Deposit date:
2022-12-07

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