Thesis
Roles of transcription factor eomesodermin in the trophectoderm and definitive endoderm lineages of the murine embryo
- Abstract:
-
Eomesodermin (Eomes), a member of the T-box family of transcription factors, is required for the specification of a multitude of lineages during mouse gastrulation. Initially it is expressed in the trophectoderm (TE) of the pre-implantation blastocyst, where it is essential for peri-implantation development. Eomes is also expressed in the post- implantation embryo, where it has a critical role in the specification of several lineages during gastrulation, including the definitive endoderm (...
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Authors
Contributors
+ Costello, I
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Contributor
+ Xypolita, M
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Contributor
+ Bikoff, E
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Contributor
ORCID:
0000-0003-3195-7246
+ Theeuwes, B
Role:
Contributor
+ Ton, M-L
Role:
Contributor
Funding
+ Wellcome Trust
More from this funder
Funder identifier:
http://dx.doi.org/10.13039/100010269
Grant:
219978/Z/19/Z
Programme:
DPhil Chromosome and Developmental Biology
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
-
English
- Keywords:
- Deposit date:
-
2023-07-05
Terms of use
- Copyright holder:
- Bisia, AM
- Copyright date:
- 2022
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