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Comparison of protein expression in human deltoideus and vastus lateralis muscles using two-dimensional gel electrophoresis.

Abstract:

We have used two-dimensional gel electrophoresis (2-DE) and mass spectrometry (MS) to study the expression of contractile and regulatory proteins in human vastus lateralis and deltoideus muscles, in order to understand protein turnover and isoform switching in muscles with the same fiber-type composition but different functional properties. We demonstrate a two- to six-fold overexpression of enzymes associated with glycolysis, the tricarboxylic acid cycle, oxidative phosphorylation, and subst...

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Publication status:
Published

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Publisher copy:
10.1002/pmic.200401183

Authors


Capitanio, D More by this author
Viganò, A More by this author
Cerretelli, P More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
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Journal:
Proteomics
Volume:
5
Issue:
10
Pages:
2577-2586
Publication date:
2005-07-05
DOI:
EISSN:
1615-9861
ISSN:
1615-9853
URN:
uuid:45b66f61-8a4d-44e4-8abe-28eaff0bf1cf
Source identifiers:
228732
Local pid:
pubs:228732

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