Procalcitonin and C-reactive protein in hospitalized adult patients with community-acquired pneumonia or exacerbation of asthma or COPD.

Journal article

BACKGROUND: Antibiotic overuse in respiratory illness is common and is associated with drug resistance and hospital-acquired infection. Biomarkers that can identify bacterial infections may reduce antibiotic prescription. We aimed to compare the usefulness of the biomarkers procalcitonin and C-reactive protein (CRP) in patients with pneumonia or exacerbations of asthma or COPD. METHODS: Patients with a diagnosis of community-acquired pneumonia or exacerbation of asthma or COPD were recruited ...

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Authors: Bafadhel, M; Clark, T; Reid, C; Medina, M; Batham, S

• Journal: Chest
• Volume: 139
• Issue: 6
• Pages: 1410-1418
• Publication date: 2011-06-01
• DOI: 10.1378/chest.10-1747
• EISSN: 1931-3543
• ISSN: 0012-3692
• Language: English
• Keywords: Hospitalization; Humans; ROC Curve; Calcitonin; Young Adult; Predictive Value of Tests; Middle Aged; Aged; Female; Asthma; Male; Protein Precursors; Biological Markers; Aged, 80 and over; Pneumonia, Bacterial; C-Reactive Protein; Adolescent; Community-Acquired Infections; Pulmonary Disease, Chronic Obstructive; Adult