- Abstract:
-
Osteoblastic stromal cells are capable of supporting osteoclast formation from hematopoietic precursors in the presence of osteotropic factors such as 1alpha,25(OH)(2)D(3), PTH, and IL-11. Osteoblastic stromal cells produce receptor activator of NF-kappaB ligand (RANKL), a type II membrane protein of the TNF ligand family, in response to these agents. Activated T lymphocytes also produce RANKL; however, the ability of this cell type to support osteoclast formation in vitro is unknown. Human P...
Expand abstract - Publisher copy:
- 10.1006/bbrc.1999.1623
-
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- Journal:
- Biochemical and biophysical research communications
- Volume:
- 265
- Issue:
- 1
- Pages:
- 144-150
- Publication date:
- 1999-11-05
- DOI:
- EISSN:
-
1090-2104
- ISSN:
-
0006-291X
- URN:
-
uuid:4571f58a-be46-4635-ae6c-196c992a4ca5
- Source identifiers:
-
429434
- Local pid:
- pubs:429434
- Language:
- English
- Keywords:
- Copyright date:
- 1999
Journal article
Activated T lymphocytes support osteoclast formation in vitro.
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