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Relationship between quality of reports of antidepressant randomized controlled trials and treatment estimates: systematic review, meta-analysis, and meta-regression analysis.

Abstract:

In the field of meta-analyses of antidepressant randomized controlled trials (RCTs), it is unclear whether a relationship exists between study quality, treatment estimates, and different quality measures. In this systematic review, we investigated whether quality of RCTs allocating patients with major depression to fluoxetine versus any other antidepressant agent influenced treatment estimates. We designed a systematic review and meta-regression analysis of RCTs, obtaining data from the Cochr...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Malvini, L More by this author
Furukawa, TA More by this author
Journal:
Journal of clinical psychopharmacology
Volume:
27
Issue:
4
Pages:
352-356
Publication date:
2007-08-05
DOI:
EISSN:
1533-712X
ISSN:
0271-0749
URN:
uuid:452edc94-d02f-47d6-be92-60a862c1229a
Source identifiers:
426037
Local pid:
pubs:426037

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