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Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort.

Abstract:

Broadly neutralizing antibodies (bnAbs) are thought to be a critical component of a protective HIV vaccine. However, designing vaccines immunogens able to elicit bnAbs has proven unsuccessful to date. Understanding the correlates and immunological mechanisms leading to the development of bnAb responses during natural HIV infection is thus critical to the design of a protective vaccine. The IAVI Protocol C program investigates a large longitudinal cohort of primary HIV-1 infection in Eastern a...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.ppat.1005369

Authors


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International AIDS Vaccine Initiative More from this funder
United States Agency for International Development (USAID) More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS pathogens Journal website
Volume:
12
Issue:
1
Pages:
e1005369
Chapter number:
ARTN e1005369
Publication date:
2016-01-14
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
URN:
uuid:45101033-828f-46fd-984d-589faa5b5b78
Source identifiers:
597813
Local pid:
pubs:597813

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