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Journal article

Cytoplasmic poly(A) polymerases mediate cellular responses to S phase arrest.

Abstract:

The S-M checkpoint delays mitosis until DNA replication is complete; cells defective in this checkpoint lose viability when DNA replication is inhibited. This inviability can be suppressed in fission yeast by overexpression of Cid1 or the related protein Cid13. Fission yeast contain six cid1/cid13-like genes, whereas budding yeast has just two, TRF4 and TRF5. Trf4 and Trf5 were recently reported to comprise an essential DNA polymerase activity required for the establishment of sister chromati...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.192467799

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
99
Issue:
19
Pages:
12079-12084
Publication date:
2002-09-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:450c1e3e-a5ca-47ce-994f-175d0eec6895
Source identifiers:
26978
Local pid:
pubs:26978

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