- Abstract:
-
Almost 8% of the human genome comprises endogenous retroviruses (ERVs). While they have been shown to cause specific pathologies in animals, such as cancer, their association with disease in humans remains controversial. The limited evidence is partly due to the physical and bioethical restrictions surrounding the study of transposons in humans, coupled with the major experimental and bioinformatics challenges surrounding the association of ERVs with disease in general. Two biotechnological l...
Expand abstract - Publication status:
- Published online
- Publisher copy:
- 10.1098/rstb.2012.0504
-
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- Journal:
- Philosophical transactions of the Royal Society of London. Series B, Biological sciences
- Volume:
- 368
- Issue:
- 1626
- Pages:
- 20120504
- Chapter number:
- ARTN 20120504
- Publication date:
- 2013-09-05
- DOI:
- EISSN:
-
1471-2970
- ISSN:
-
0962-8436
- URN:
-
uuid:44eef38d-36b5-4008-b2a2-0a8f78a94755
- Source identifiers:
-
418317
- Local pid:
- pubs:418317
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
'There and back again': revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic era.
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