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Journal article

Alternative Runx1 promoter usage in mouse developmental hematopoiesis.

Abstract:

The interest in stem cell based therapies has emphasized the importance of understanding the cellular and molecular mechanisms by which stem cells are generated in ontogeny and maintained throughout adult life. Hematopoietic stem cells (HSCs) are first found in clusters of hematopoietic cells budding from the luminal wall of the major arteries in the developing mammalian embryo. The transcription factor Runx1 is critical for their generation and is specifically expressed at sites of HSC gener...

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Publication status:
Published

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Publisher copy:
10.1016/j.bcmd.2009.03.011

Authors


Liddiard, K More by this author
Bickley, SR More by this author
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Journal:
Blood cells, molecules and diseases
Volume:
43
Issue:
1
Pages:
35-42
Publication date:
2009
DOI:
EISSN:
1096-0961
ISSN:
1079-9796
URN:
uuid:44ee7c38-9ae3-48e9-bbfe-4f6de42c43e8
Source identifiers:
273366
Local pid:
pubs:273366

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