- Abstract:
-
Graves' disease (GD) and Hashimoto's thyroiditis (HT) make up the autoimmune thyroid diseases (AITD), with classical clinical characteristics arising as a result of environmental factors in people who are genetically predisposed. Three gene regions consistently associated with AITD include the Human Leucocyte Antigen (HLA) region, CTLA4 and PTPN22, which represent general autoimmune risk loci and encode molecules vital for correct immune system function. AITD patients in addition are likely t...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.mce.2010.01.013
-
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- Journal:
- Molecular and cellular endocrinology
- Volume:
- 322
- Issue:
- 1-2
- Pages:
- 135-143
- Publication date:
- 2010-06-05
- DOI:
- EISSN:
-
1872-8057
- ISSN:
-
0303-7207
- URN:
-
uuid:44d2ab2e-674f-4041-ae1d-e60caef338c0
- Source identifiers:
-
176424
- Local pid:
- pubs:176424
- Copyright date:
- 2010
Journal article
Genetics of thyroid autoimmunity and the role of the TSHR.
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