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Investigation of sperm telomere length as a potential marker of paternal genome integrity and semen quality

Abstract:

Recent studies have reported shorter sperm telomere length (STL) in men with idiopathic infertility. The aim of this study was to measure STL in semen samples from men to evaluate whether STL variation is associated with chromosomal abnormality, DNA fragmentation, traditional semen parameters, IVF outcome, or all four factors. A significant correlation between telomere length and diploidy was observed (P = 0.037). Additionally, STL was found to be positively associated with sperm count (P = 0...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.rbmo.2016.06.006

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Publisher:
Elsevier Publisher's website
Journal:
Reproductive BioMedicine Online Journal website
Volume:
33
Issue:
3
Pages:
404-411
Publication date:
2016-06-27
Acceptance date:
2016-06-15
DOI:
EISSN:
1472-6491
ISSN:
1472-6483
Pubs id:
pubs:568033
URN:
uri:44c1778a-1935-4ffa-b597-e0c97c6d14f9
UUID:
uuid:44c1778a-1935-4ffa-b597-e0c97c6d14f9
Local pid:
pubs:568033

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