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Ponsin interacts with Nck adapter proteins: implications for a role in cytoskeletal remodelling during differentiation of skeletal muscle cells.

Abstract:

Skeletal muscle differentiation is a complex process: It is characterised by changes in gene expression and protein composition. Simultaneously, a dramatic remodelling of the cytoskeleton and associated cell-matrix contacts, the costameres, occurs. The expression and localisation of the protein ponsin at cell-matrix contacts marks the establishment of costameres. In this report we show that skeletal muscle cells are characterised by a novel ponsin isoform, which contains a large insertion in ...

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Publisher copy:
10.1016/j.ejcb.2009.10.019

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
Van der Ven, PF More by this author
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Journal:
European journal of cell biology
Volume:
89
Issue:
5
Pages:
351-364
Publication date:
2010-05-05
DOI:
EISSN:
1618-1298
ISSN:
0171-9335
URN:
uuid:44a56e04-bf94-4952-9ebc-4a934bfc0a59
Source identifiers:
267752
Local pid:
pubs:267752

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