The use of PET images for radiotherapy treatment planning: an error analysis using radiobiological endpoints.
PURPOSE: There is significant current interest in the use of biological image guidance in radiotherapy planning. In lung-cancer treatment, tumor motion due to respiration is known to be a limitation. This is particularly true in PET, where image data are collected over a number of minutes. An in-house-developed 4D PET acquisition mode is described and an analysis of the effects of acquisition parameters on the reconstructed image quality is presented. The potential impact of the resulting bio...Expand abstract
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