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Journal article

Therapeutic vaccination to block receptor-ligand interactions.

Abstract:

Many chronic diseases are caused by non-physiological interactions of certain ligands with their receptors. Conventional treatment of these diseases with synthetic drugs or monoclonal antibodies (mAbs) is efficient, but problematic due to the non-compliance of patients and the risk of adverse side effects. Novel therapeutic approaches are focusing on strategies of active immunisation aimed at the induction of a humoral immune response directed against the deleterious receptor-ligand interacti...

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Publication status:
Published

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Publisher copy:
10.1517/14712598.3.3.469

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Role:
Author
Journal:
Expert opinion on biological therapy
Volume:
3
Issue:
3
Pages:
469-476
Publication date:
2003-06-05
DOI:
EISSN:
1744-7682
ISSN:
1471-2598
URN:
uuid:4497da25-1d7f-4489-9a45-bab87d3d2e22
Source identifiers:
469740
Local pid:
pubs:469740

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