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Journal article

Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3.

Abstract:

The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. XFLRT3, a Nodal/TGFbeta target, regulates cell adhesion and modulates FGF signalling during Xenopus gastrulation. The present study describes the onset and pattern of FLRT1-3 expression in the early mouse embryo. FLRT3 expression is activated in the anterior visceral endoderm (AVE)...

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Publication status:
Published

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Publisher copy:
10.1016/j.ydbio.2008.03.021

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
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Journal:
Developmental biology
Volume:
318
Issue:
1
Pages:
184-193
Publication date:
2008-06-01
DOI:
EISSN:
1095-564X
ISSN:
0012-1606
Source identifiers:
15484

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