- Abstract:
-
The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. XFLRT3, a Nodal/TGFbeta target, regulates cell adhesion and modulates FGF signalling during Xenopus gastrulation. The present study describes the onset and pattern of FLRT1-3 expression in the early mouse embryo. FLRT3 expression is activated in the anterior visceral endoderm (AVE)...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.ydbio.2008.03.021
-
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- Journal:
- Developmental biology
- Volume:
- 318
- Issue:
- 1
- Pages:
- 184-193
- Publication date:
- 2008-06-05
- DOI:
- EISSN:
-
1095-564X
- ISSN:
-
0012-1606
- URN:
-
uuid:4497cd13-b36c-4aec-8745-8c4d006e1286
- Source identifiers:
-
15484
- Local pid:
- pubs:15484
- Language:
- English
- Keywords:
- Copyright date:
- 2008
Journal article
Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3.
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