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A functional magnetic resonance imaging study of verbal working memory in young people at increased familial risk of depression

Abstract:
Background: Patients with depression show abnormalities in the neural circuitry supporting working memory. These abnormalities apparently persist into clinical remission, raising the possibility that they might be trait markers indicating vulnerability to depression. Methods: We studied 17 young people who had a depressed parent but no personal history of depressive illness (FH) and 15 healthy control subjects with no family history of depression. Participant... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Research group:
Psychopharmacology Research Unit
Department:
Medical Sciences Division - Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Medical Sciences Division - Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Research group:
Psychopharmacology Research Unit
Department:
Medical Sciences Division - Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Medical Sciences Division - Psychiatry
Role:
Author
More from this funder
Funding agency for:
Philip J. Cowen
Medical Research Council More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Biological Psychiatry Journal website
Volume:
67
Issue:
5
Pages:
471-477
Publication date:
2010-03-05
DOI:
ISSN:
0006-3223
URN:
uuid:44912dfd-ad06-4058-aa73-2d185751fe27
Local pid:
ora:3484
Language:
English
Keywords:
Subjects:

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