Thesis
The energetics of nucleotide binding to RAS proteins
- Abstract:
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Ras proteins are a special class of proteins that mediate cell growth signals. Their importance lies in the fact that they are products of a proto-oncogene. This means that under certain conditions the gene that determines its structure is altered and a mutant protein results that is involved in the transformation of normal cells to cancer cells.
The actual function by which the protein acts in the signal pathway is not known. However it is known that they act as a switch,...
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Bibliographic Details
- Publication date:
- 1992
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Source identifiers:
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603840939
Item Description
- Language:
- English
- Subjects:
- UUID:
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uuid:44524415-2f2b-4601-998c-56110f332153
- Local pid:
- td:603840939
- Deposit date:
- 2013-06-22
Terms of use
- Copyright holder:
- Graham A. Worth
- Copyright date:
- 1992
- Notes:
- The digital copy of this thesis has been made available thanks to the generosity of Dr Leonard Polonsky
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