- Abstract:
-
Matrix proteins associated with the viral membrane are important in the formation of the viral particle and in virus maturation. The 1.0 A crystal structure of the ecotropic Gammaretrovirus Moloney murine leukemia virus (M-MuLV) matrix protein reveals the conserved topology of other retroviral matrix proteins, despite undetectable sequence similarity. The N terminus (normally myristylated) is exposed and adjacent to a basic surface patch, features likely to contribute to membrane binding. The...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/s0969-2126(02)00896-1
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- Journal:
- Structure (London, England : 1993)
- Volume:
- 10
- Issue:
- 12
- Pages:
- 1627-1636
- Publication date:
- 2002-12-05
- DOI:
- EISSN:
-
1878-4186
- ISSN:
-
0969-2126
- URN:
-
uuid:44274a2e-1df6-4c85-8134-cdbcfea622ab
- Source identifiers:
-
449399
- Local pid:
- pubs:449399
- Copyright date:
- 2002
Journal article
Atomic resolution structure of Moloney murine leukemia virus matrix protein and its relationship to other retroviral matrix proteins.
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