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Dyneins across eukaryotes: a comparative genomic analysis.

Abstract:

Dyneins are large minus-end-directed microtubule motors. Each dynein contains at least one dynein heavy chain (DHC) and a variable number of intermediate chains (IC), light intermediate chains (LIC) and light chains (LC). Here, we used genome sequence data from 24 diverse eukaryotes to assess the distribution of DHCs, ICs, LICs and LCs across Eukaryota. Phylogenetic inference identified nine DHC families (two cytoplasmic and seven axonemal) and six IC families (one cytoplasmic). We confirm th...

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Publication status:
Published

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Authors


Wickstead, B More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Traffic (Copenhagen, Denmark)
Volume:
8
Issue:
12
Pages:
1708-1721
Publication date:
2007-12-05
DOI:
EISSN:
1600-0854
ISSN:
1398-9219
URN:
uuid:44113936-03c6-490b-a18f-ff127845896f
Source identifiers:
21738
Local pid:
pubs:21738

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