Journal article
Overcoming the challenges of membrane protein crystallography.
- Abstract:
-
Membrane protein structural biology is still a largely unconquered area, given that approximately 25% of all proteins are membrane proteins and yet less than 150 unique structures are available. Membrane proteins have proven to be difficult to study owing to their partially hydrophobic surfaces, flexibility and lack of stability. The field is now taking advantage of the high-throughput revolution in structural biology and methods are emerging for effective expression, solubilisation, purifica...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.sbi.2008.07.001
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Bibliographic Details
- Journal:
- Current opinion in structural biology
- Volume:
- 18
- Issue:
- 5
- Pages:
- 581-586
- Publication date:
- 2008-10-01
- DOI:
- EISSN:
-
1879-033X
- ISSN:
-
0959-440X
- Source identifiers:
-
72730
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:72730
- UUID:
-
uuid:440186a7-c02f-41e9-9209-11db65ff358e
- Local pid:
- pubs:72730
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2008
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