- Abstract:
-
Membrane protein structural biology is still a largely unconquered area, given that approximately 25% of all proteins are membrane proteins and yet less than 150 unique structures are available. Membrane proteins have proven to be difficult to study owing to their partially hydrophobic surfaces, flexibility and lack of stability. The field is now taking advantage of the high-throughput revolution in structural biology and methods are emerging for effective expression, solubilisation, purifica...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.sbi.2008.07.001
-
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- Journal:
- Current opinion in structural biology
- Volume:
- 18
- Issue:
- 5
- Pages:
- 581-586
- Publication date:
- 2008-10-05
- DOI:
- EISSN:
-
1879-033X
- ISSN:
-
0959-440X
- URN:
-
uuid:440186a7-c02f-41e9-9209-11db65ff358e
- Source identifiers:
-
72730
- Local pid:
- pubs:72730
- Copyright date:
- 2008
Journal article
Overcoming the challenges of membrane protein crystallography.
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