Journal article
Increased substitution rates surrounding low-complexity regions within primate proteins.
- Abstract:
-
Previous studies have found that DNA-flanking low-complexity regions (LCRs) have an increased substitution rate. Here, the substitution rate was confirmed to increase in the vicinity of LCRs in several primate species, including humans. This effect was also found among human sequences from the 1000 Genomes Project. A strong correlation was found between average substitution rate per site and distance from the LCR, as well as the proportion of genes with gaps in the alignment at each site and ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1093/gbe/evu042
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Authors
Bibliographic Details
- Publisher:
- Oxford University Press
- Journal:
- Genome biology and evolution
- Volume:
- 6
- Issue:
- 3
- Pages:
- 655-665
- Publication date:
- 2014-03-01
- DOI:
- EISSN:
-
1759-6653
- ISSN:
-
1759-6653
- Source identifiers:
-
450948
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:450948
- UUID:
-
uuid:43c45803-f95f-422c-a3f1-fa7439d66b21
- Local pid:
- pubs:450948
- Deposit date:
- 2014-07-02
Terms of use
- Copyright date:
- 2014
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