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Journal article

Anion sensitivity and spectral tuning of middle- and long-wavelength-sensitive (MWS/LWS) visual pigments.

Abstract:

The long-wavelength-sensitive (LWS) opsins form one of four classes of vertebrate cone visual pigment and exhibit peak spectral sensitivities (λ(max)) that generally range from 525 to 560 nm for rhodopsin/vitamin-A(1) photopigments. Unique amongst the opsin classes, many LWS pigments show anion sensitivity through the interaction of chloride ions with a histidine residue at site 197 (H197) to give a long-wavelength spectral shift in peak sensitivity. Although it has been shown that amino acid...

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Publication status:
Published

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Publisher copy:
10.1007/s00018-012-0934-4

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
Cellular and molecular life sciences : CMLS
Volume:
69
Issue:
14
Pages:
2455-2464
Publication date:
2012-07-05
DOI:
EISSN:
1420-9071
ISSN:
1420-682X
URN:
uuid:43ba772c-b49e-4fad-8e23-c205dc32c821
Source identifiers:
312889
Local pid:
pubs:312889

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