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Molecular staging using qualitative RT-PCR analysis detecting thyreoglobulin mRNA in the peripheral blood of patients with differentiated thyroid cancer after therapy.

Abstract:

BACKGROUND: The prognostic significance of molecular staging using thyroglobulin (Tg)-based RT-PCR analysis in the peripheral blood of patients with differentiated thyroid cancer (DTC) was investigated. Herein, the specificity of molecular staging in DTC patients after thyroidectomy and 131I ablation therapy was analysed, using different specific cDNA primers in qualitative nested and classical RT-PCR protocols. PATIENTS AND METHODS: Ninty-five patients receiving TSH suppressive therapy were...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
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Journal:
Anticancer research
Volume:
25
Issue:
4
Pages:
3135-3142
Publication date:
2005-01-01
EISSN:
1791-7530
ISSN:
0250-7005
URN:
uuid:43b0cd8b-8410-4b53-8510-f559412a508d
Source identifiers:
111380
Local pid:
pubs:111380

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