Journal article
Sonodynamic therapy complements PD-L1 immune checkpoint inhibition in a murine model of pancreatic cancer
- Abstract:
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The emergence of immune checkpoint inhibitors (ICI's) in the past decade has proven transformative in the area of immuno-oncology. The PD-1/PD-L1 axis has been particularly well studied and monoclonal antibodies developed to block either the receptor (anti PD-1) or its associated ligand (anti PD-L1) can generate potent anti-tumour immunity in certain tumour models. However, many "immune cold" tumours remain unresponsive to ICI's and strategies to stimulate the adaptive immune system and make ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Accepted manuscript, 771.8KB, Terms of use)
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- Publisher copy:
- 10.1016/j.canlet.2021.06.003
Authors
Bibliographic Details
- Publisher:
- Elsevier
- Journal:
- Cancer Letters More from this journal
- Volume:
- 517
- Pages:
- 88-95
- Publication date:
- 2021-06-10
- Acceptance date:
- 2021-06-07
- DOI:
- EISSN:
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1872-7980
- ISSN:
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0304-3835
- Pmid:
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34119606
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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1182487
- Local pid:
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pubs:1182487
- Deposit date:
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2021-08-04
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2021
- Rights statement:
- © 2021 Elsevier B.V. All rights reserved.
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.canlet.2021.06.003
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