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Effects of brain death on donor organ viability

Abstract:

Recently it has become clear that, in addition to ischemia/reperfusion injury and posttransplant recipient-related factors, the induction of brain death would be a significant risk factor for posttransplant graft dysfunction. Brain death-related systemic changes and their effect on the hormonal and hemodynamic condition of the donor have been previously described. Now, an antigen-independent immunologic tissue activation in potential donor organs has been observed. In animal models this tissu...

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
Journal:
Current Opinion in Organ Transplantation
Volume:
6
Issue:
1
Pages:
75-82
Publication date:
2001-01-01
DOI:
ISSN:
1087-2418
URN:
uuid:43a822b4-3655-4eb1-ae2a-f6094ba15aeb
Source identifiers:
191045
Local pid:
pubs:191045
Language:
English

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