Journal article icon

Journal article

Continuous administration of human corticotropin-releasing hormone in the absence of glucocorticoid feedback in man.

Abstract:

Continuous 24-hour infusions of a maximally stimulating dose (1 microgram/kg/h) of corticotropin-releasing hormone (CRH) have been shown to cause elevations of plasma cortisol and ACTH, but the pattern of results were confounded by serum cortisol causing feedback changes. We have looked at ACTH responses to saline or CRH infusions over 24 h in 6 normal subjects who, in addition, received either placebo or metyrapone, an 11 beta-hydroxylase inhibitor which blocks the formation of cortisol and ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1159/000126840

Authors


Capstick, C More by this author
McLoughlin, L More by this author
Checkley, S More by this author
Besser, GM More by this author
Expand authors...
Journal:
Neuroendocrinology
Volume:
61
Issue:
2
Pages:
191-197
Publication date:
1995-02-05
DOI:
EISSN:
1423-0194
ISSN:
0028-3835
URN:
uuid:432c3c66-6690-4be5-ac52-de4fd6c20304
Source identifiers:
138490
Local pid:
pubs:138490

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP