Journal article
Metalloproteinase binding proteins: WO2009097397.
- Abstract:
-
MMPs are a group of metalloendopeptidases whose major role is in extracellular matrix (ECM) catabolism under physiological and pathological conditions. ECM catabolism is often associated with different diseases, and accumulated studies support the causal relationship between MMPs and different diseases especially with cancer and arthritis. Therefore, MMPs have been considered as therapeutic target molecules. However, multiple failures of MMP inhibitor drugs in clinical trials from late 1990s ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1517/13543776.2010.488221
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Bibliographic Details
- Journal:
- Expert opinion on therapeutic patents
- Volume:
- 20
- Issue:
- 8
- Pages:
- 1091-1095
- Publication date:
- 2010-08-05
- DOI:
- EISSN:
-
1744-7674
- ISSN:
-
1354-3776
- URN:
-
uuid:432ab6df-15a9-4d1d-b84a-7cdfcb10e81c
- Source identifiers:
-
223989
- Local pid:
- pubs:223989
Item Description
Terms of use
- Copyright date:
- 2010
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