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Journal article

CYP3A variation, premenopausal estrone levels, and breast cancer risk.

Abstract:

BACKGROUND: Epidemiological studies have provided strong evidence for a role of endogenous sex steroids in the etiology of breast cancer. Our aim was to identify common variants in genes involved in sex steroid synthesis or metabolism that are associated with hormone levels and the risk of breast cancer in premenopausal women. METHODS: We measured urinary levels of estrone glucuronide (E1G) using a protocol specifically developed to account for cyclic variation in hormone levels during the me...

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Publication status:
Published

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Publisher copy:
10.1093/jnci/djs156

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Journal:
Journal of the National Cancer Institute
Volume:
104
Issue:
9
Pages:
657-669
Publication date:
2012-05-05
DOI:
EISSN:
1460-2105
ISSN:
0027-8874
URN:
uuid:430fcfc6-fe57-4aa0-8f7d-edbe5a2fed0b
Source identifiers:
322676
Local pid:
pubs:322676

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