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Genetic polymorphisms in the circumsporozoite protein of Plasmodium malariae show a geographical bias

Abstract:

Background

Plasmodium malariae is characterized by its long asymptomatic persistence in the human host. The epidemiology of P. malariae is incompletely understood and is hampered by the limited knowledge of genetic polymorphisms. Previous reports from Africa have shown heterogeneity within the P. malariae circumsporozoite protein (pmcsp) gene. However, comparative studies from Asian countries are lacking. Here, the genetic polymorphisms in pmcsp of Asian isolates have been charac...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s12936-018-2413-3

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Oxford college:
Nuffield College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Role:
Author
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Wellcome Trust More from this funder
Mahidol University More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Malaria Journal Journal website
Volume:
17
Issue:
1
Pages:
269
Publication date:
2018-07-16
Acceptance date:
2018-07-09
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
Pubs id:
pubs:891176
URN:
uri:42f5deef-3a25-4cf2-b384-2e7ea826ccdb
UUID:
uuid:42f5deef-3a25-4cf2-b384-2e7ea826ccdb
Local pid:
pubs:891176

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