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Journal article

Severe atopic dermatitis is associated with a reduced frequency of IL-10 producing allergen-specific CD4+ T cells.

Abstract:

BACKGROUND: Several studies have investigated levels of T-cell-derived interleukin (IL)-10 in individuals with atopic dermatitis, with conflicting results. AIMS/HYPOTHESIS: In order to address whether stratification of disease severity may help resolve the different findings, the hypothesis was tested that individuals with severe atopic dermatitis have a lower frequency of circulating IL-10-producing, allergen-specific CD4+ T cells than do individuals with mild disease. METHODS: Using periphe...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-CTU
Role:
Author
Journal:
Clinical and experimental dermatology
Volume:
31
Issue:
5
Pages:
689-694
Publication date:
2006-09-05
DOI:
EISSN:
1365-2230
ISSN:
0307-6938
URN:
uuid:42f1d7e5-8711-43fc-8176-410030a447e1
Source identifiers:
27315
Local pid:
pubs:27315

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