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ISOLATION OF DIHYDROCLAVAMINIC ACID, AN INTERMEDIATE IN THE BIOSYNTHESIS OF CLAVULANIC ACID

Abstract:
A primary isotope effect was utilised in an in vitro study to allow the isolation and characterisation of an intermediate between proclavaminic acid and clavaminic acid, in clavulanic acid biosynthesis.1 1 For preliminary details see J. E. Baldwin, R. M. Adlington, J. S. Bryans, A. O. Bringhen, J. B. Coates, N. P. Crouch, M. D. Lloyd, C. J. Schofield. S. W. Elson, K. H. Baggaley, R. Cassells, and N. H. Nicholson, J. Chem. Soc. Chem. Commun., 1990, 617. © 1991.
Publication status:
Published

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Journal:
TETRAHEDRON
Volume:
47
Issue:
24
Pages:
4089-4100
Publication date:
1991-06-10
DOI:
ISSN:
0040-4020
URN:
uuid:42ea22a6-ff22-4e53-b531-0470416b50f3
Source identifiers:
43599
Local pid:
pubs:43599

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