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Bilateral adaptive deep brain stimulation is effective in Parkinson's disease

Abstract:
Introduction and objectives: Adaptive deep brain stimulation (aDBS) uses feedback from brain signals to guide stimulation. A recent acute trial of unilateral aDBS showed that aDBS can lead to substantial improvements in contralateral hemibody Unified Parkinson’s Disease Rating Scale (UPDRS) motor scores and may be superior to conventional continuous DBS in Parkinson’s disease (PD). We test whether potential benefits are retained with bilateral aDBS and in the face of concurre... Expand abstract
Publication status:
In press
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/jnnp-2015-310972

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Medical Research Council More from this funder
National Institute for Health Research Oxford Biomedical Research Centre More from this funder
Rosetrees Trust More from this funder
Publisher:
BMJ Publishing Group Publisher's website
Journal:
Journal of Neurology, Neurosurgery and Psychiatry Journal website
Publication date:
2015-01-01
DOI:
EISSN:
1468-330X
ISSN:
0022-3050
Source identifiers:
574364
Pubs id:
pubs:574364
UUID:
uuid:42e97ff8-a7b2-4063-8b29-e992cf74aa13
Local pid:
pubs:574364
Deposit date:
2015-11-17

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