- Abstract:
-
Introduction and objectives: Adaptive deep brain stimulation (aDBS) uses feedback from brain signals to guide stimulation. A recent acute trial of unilateral aDBS showed that aDBS can lead to substantial improvements in contralateral hemibody Unified Parkinson’s Disease Rating Scale (UPDRS) motor scores and may be superior to conventional continuous DBS in Parkinson’s disease (PD). We test whether potential benefits are retained with bilateral aDBS and in the face of concurre... Expand abstract
- Publication status:
- In press
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Publisher:
- BMJ Publishing Group Publisher's website
- Journal:
- Journal of Neurology, Neurosurgery and Psychiatry Journal website
- Publication date:
- 2015
- DOI:
- EISSN:
-
1468-330X
- ISSN:
-
0022-3050
- URN:
-
uuid:42e97ff8-a7b2-4063-8b29-e992cf74aa13
- Source identifiers:
-
574364
- Local pid:
- pubs:574364
- Copyright holder:
- Little et al.
- Copyright date:
- 2015
- Notes:
- This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
Journal article
Bilateral adaptive deep brain stimulation is effective in Parkinson's disease
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Funding
Medical Research Council
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Rosetrees Trust
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National Institute for Health Research Oxford Biomedical
Research Centre
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