Journal article icon

Journal article

Reduction in occipital cortex gamma-aminobutyric acid concentrations in medication-free recovered unipolar depressed and bipolar subjects.

Abstract:

BACKGROUND: Studies using proton magnetic resonance spectroscopy (MRS) have indicated that unmedicated, acutely depressed patients have decreased levels of gamma-aminobutyric acid (GABA) in occipital cortex. Cortical levels of glutamate (Glu) may be increased, although these data are less consistent. The aim of this study was to use MRS to determine whether changes in GABA and Glu levels were present in patients with mood disorders who had recovered and were no longer taking medication. METHO...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Bhagwagar, Z More by this author
Wylezinska, M More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Ashworth, F More by this author
Expand authors...
Journal:
Biological psychiatry
Volume:
61
Issue:
6
Pages:
806-812
Publication date:
2007-03-05
DOI:
EISSN:
1873-2402
ISSN:
0006-3223
URN:
uuid:42c9a3e9-0db7-4fde-8886-5379348d3ad2
Source identifiers:
139925
Local pid:
pubs:139925

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP