Journal article icon

Journal article

Loss of heterozygosity studies at the retinoblastoma and breast cancer susceptibility (BRCA2) loci in pituitary, parathyroid, pancreatic and carcinoid tumours.

Abstract:

OBJECTIVE: Allelic deletion of the retinoblastoma (Rb) gene on chromosome 13 has been reported in both pituitary and parathyroid tumours. We have investigated the roles of the Rb and the hereditary breast cancer susceptibility gene (BRCA2), which lie within 25 cM of each other on chromosome 13q12-14, in the multi-step aetiology of endocrine tumours. PATIENTS AND MEASUREMENTS: Seventy-seven endocrine tumours (43 anterior pituitary, 22 parathyroid, 7 carcinoid, and 5 pancreatic islet cell tumou...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Pearce, SH More by this author
Wooding, C More by this author
Sheppard, MN More by this author
Clayton, RN More by this author
Expand authors...
Journal:
Clinical endocrinology
Volume:
45
Issue:
2
Pages:
195-200
Publication date:
1996-08-05
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
URN:
uuid:42a1f201-21ec-4964-96c2-740dde38a2ef
Source identifiers:
30550
Local pid:
pubs:30550

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP