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A workflow for the detection of antibiotic residues, measurement of water chemistry and preservation of hospital sink drain samples for metagenomic sequencing

Abstract:

Background: Hospital sinks are environmental reservoirs that harbour healthcare-associated (HCA) pathogens. Selective pressures in sink environments, such as antibiotic residues, nutrient waste and hardness ions, may promote antibiotic resistance gene (ARG) exchange between bacteria. However, cheap and accurate sampling methods to characterise these factors are lacking.

Aim: To validate a workflow to detect antibiotic residues and evaluate water ch...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jhin.2023.11.021

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
ORCID:
0000-0002-6926-080X
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Publisher:
Elsevier
Journal:
Journal of Hospital Infection More from this journal
Volume:
144
Pages:
128-136
Publication date:
2023-12-23
Acceptance date:
2023-12-01
DOI:
ISSN:
0195-6701
Language:
English
Keywords:
Pubs id:
1598138
Local pid:
pubs:1598138
Deposit date:
2024-01-09

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