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Journal article

Inflammatory signalling as mediator of epigenetic modulation in tissue-specific chronic inflammation.

Abstract:

Recent successes of therapeutic intervention in chronic inflammatory diseases using epigenetic modifiers such as histone deacetylase inhibitors and inhibitors of DNA methylation suggest that epigenetic reprogramming plays a role in the aetiology of these diseases. The epigenetic signature of a given immune cell is reflected in the history of modifications from different signals the cell has been subjected to during differentiation. Like other cells, differentiating immune cells are dependent ...

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Publication status:
Published

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Authors


Bäckdahl, L More by this author
Bushell, A More by this author
Journal:
The international journal of biochemistry and cell biology
Volume:
41
Issue:
1
Pages:
176-184
Publication date:
2009-01-05
DOI:
EISSN:
1878-5875
ISSN:
1357-2725
URN:
uuid:428407e9-1206-461e-988e-8be5b2eb106f
Source identifiers:
252280
Local pid:
pubs:252280

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