Effect of protocatechuic acid from Alpinia oxyphylla on proliferation of human adipose tissue-derived stromal cells in vitro.

Journal article

The effect of protocatechuic acid (PCA) from Alpinia oxyphylla and catapol from Rehmannia on the proliferation capacity of human adipose tissue-derived stromal cells (hADSCs) was investigated in vitro. Cell counts showed that treatment of hADSCs with PCA for 48 h increased the cell number in a dose-dependent manner, while no obvious effect of catapol on the proliferation of hADSCs was observed. In addition, the cell number of hADSCs treated by 1.5 mM PCA increased in a time-dependent manner. ...

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Authors: Wang, H; Liu, T; Zhu, Y; Guan, S; Ma, X

• Publication status: Published
• Journal: Molecular and cellular biochemistry
• Volume: 330
• Issue: 1-2
• Pages: 47-53
• Publication date: 2009-10-01
• DOI: 10.1007/s11010-009-0099-0
• EISSN: 1573-4919
• ISSN: 0300-8177
• Language: English
• Keywords: Rehmannia; Cell Proliferation; Multipotent Stem Cells; Hydroxybenzoates; Cells, Cultured; Stromal Cells; Dose-Response Relationship, Drug; Mesenchymal Stromal Cells; Quaternary Ammonium Compounds; Humans; Cyclin D1; Cell Cycle; Alpinia; Adipose Tissue; Kinetics