Journal article icon

Journal article

Therapeutic gene silencing in the nervous system.

Abstract:

Progress in the understanding of RNA biology has brought into focus the prospect of using RNA-based therapeutics as a novel approach to treat human disease. In particular, following the discovery of the RNA interference (RNAi) pathway, the emergence of technology based on small interfering RNA (siRNA) now offers a powerful and highly specific tool for therapeutic gene silencing. Many neurological diseases, including neurodegenerative disorders, tumours and retinal disease are likely candidate...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/hmg/ddg275

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Trülzsch, B More by this author
Abdelgany, A More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Molecular Medicine
Journal:
Human molecular genetics
Volume:
12 Spec No 2
Issue:
REV. ISS. 2
Pages:
R279-R284
Publication date:
2003-10-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:42589090-c726-44c4-97aa-e09c9a22da00
Source identifiers:
114099
Local pid:
pubs:114099

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP