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Fluoromethylated derivatives of carnitine biosynthesis intermediates--synthesis and applications.

Abstract:
A convenient method for the synthesis of fluoromethylated carnitine biosynthesis intermediates, i.e. fluorinated derivatives of γ-butyrobetaine and trimethyllysine, is described. The fluoromethylated probes were useful in both in vitro and cell based assays employing (19)F NMR and LC-MS analyses.
Publication status:
Published

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Publisher copy:
10.1039/c3cc47581f

Authors


Rydzik, AM More by this author
Thalhammer, A More by this author
Kochan, GT More by this author
Claridge, TD More by this author
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Journal:
Chemical communications (Cambridge, England)
Volume:
50
Issue:
10
Pages:
1175-1177
Publication date:
2014-02-05
DOI:
EISSN:
1364-548X
ISSN:
1359-7345
URN:
uuid:4231ff18-ca0b-4c16-8bfb-6b4c6e433662
Source identifiers:
441763
Local pid:
pubs:441763

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