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A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer.

Abstract:

Estrogen receptor (ER)-negative breast cancer shows a higher incidence in women of African ancestry compared to women of European ancestry. In search of common risk alleles for ER-negative breast cancer, we combined genome-wide association study (GWAS) data from women of African ancestry (1,004 ER-negative cases and 2,745 controls) and European ancestry (1,718 ER-negative cases and 3,670 controls), with replication testing conducted in an additional 2,292 ER-negative cases and 16,901 controls...

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Publication status:
Published

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Publisher copy:
10.1038/ng.985

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Journal:
Nature genetics
Volume:
43
Issue:
12
Pages:
1210-1214
Publication date:
2011-12-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:421ac0c4-2815-49c5-8696-8960745b25c7
Source identifiers:
216537
Local pid:
pubs:216537

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