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The role of intermediate filament proteins in the development of neurological disease.

Abstract:

Intermediate filaments (IFs), along with microfilaments and microtubules, comprise the three intracellular filaments identified in eukaryotic cells to date. Together, these three distinct filamentous networks act in a dynamic and tightly interconnected fashion to comprise the eukaryotic cytoskeleton. As such, they are involved in a number of essential and diverse cellular processes, including division, molecular transport, and the maintenance of structural integrity in the face of mechanical ...

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Journal:
Critical reviews in neurobiology
Volume:
19
Issue:
1
Pages:
1-27
Publication date:
2007
DOI:
ISSN:
0892-0915
URN:
uuid:4219d50f-d8ff-40aa-8a64-e8bac09a03f3
Source identifiers:
106438
Local pid:
pubs:106438

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