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Estimated glomerular filtration rate and the risk of major vascular events and all-cause mortality: a meta-analysis.

Abstract:

BACKGROUND: Lower estimated glomerular filtration rate (eGFR) has been associated with an increased risk of major vascular events (MVEs) and death, but differences in methodology make between-study comparisons difficult. We used a novel method to summarise the published results. METHODS AND FINDINGS: Studies assessing the relationship between baseline eGFR and subsequent MVEs or all cause mortality were identified using Pubmed. Those which involved at least 500 individuals, planned at least 1...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0025920

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Institution:
University of Oxford
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Clinical Trial Service Unit, BHF Centre of Research Excellence
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit, BHF Centre of Research Excellence
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Clinical Trial Service Unit, BHF Centre of Research Excellence
British Heart Foundation Centre of Research Excellence, Oxford More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
6
Issue:
10
Pages:
Article: e25920
Publication date:
2011
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:420d12e4-d251-462e-92dd-bb257de63118
Source identifiers:
198756
Local pid:
pubs:198756

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