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A randomized, double-blind, placebo-controlled trial of the use of prednisolone as an adjunct to treatment in HIV-1-associated pleural tuberculosis.

Abstract:

BACKGROUND: Active tuberculosis may accelerate progression of human immunodeficiency virus (HIV) infection by promoting viral replication in activated lymphocytes. Glucocorticoids are used in pleural tuberculosis to reduce inflammation-induced pathology, and their use also might reduce progression of HIV by suppressing immune activation. We examined the effect that prednisolone has on survival in HIV-1-associated pleural tuberculosis. METHODS: We conducted a randomized, double-blind, placebo...

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Publication status:
Published

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Publisher copy:
10.1086/422257

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
NPEU
Role:
Author
Host title:
The Journal of infectious diseases
Volume:
190
Issue:
5
Pages:
869-878
Publication date:
2004-09-01
Event location:
United States
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Keywords:
Pubs id:
pubs:484175
UUID:
uuid:420cb81d-eed0-40cb-ac55-d67205a2299a
Local pid:
pubs:484175
Source identifiers:
484175
Deposit date:
2014-09-18

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