Journal article
NMDA receptor-dependent long-term potentiation in mouse hippocampal interneurons shows a unique dependence on Ca(2+)/calmodulin-dependent kinases.
- Abstract:
-
Long-term potentiation (LTP) of excitatory synaptic transmission plays a major role in memory encoding in the cerebral cortex. It can be elicited at many synapses on principal cells, where it depends on Ca(2+) influx through postsynaptic N-methyl-D-aspartic acid (NMDA) receptors. Ca(2+) influx triggers phosphorylation of several kinases, in particular Ca(2+)/calmodulin-dependent kinase type II (CaMKII). Auto-phosphorylation of CaMKII is a key step in the LTP induction cascade, as revealed by ...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- Journal of physiology
- Volume:
- 584
- Issue:
- Pt 3
- Pages:
- 885-894
- Publication date:
- 2007-11-01
- DOI:
- EISSN:
-
1469-7793
- ISSN:
-
0022-3751
- Source identifiers:
-
222062
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:222062
- UUID:
-
uuid:41c6bb01-2e8b-4e85-b867-7b4cc26552ad
- Local pid:
- pubs:222062
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2007
If you are the owner of this record, you can report an update to it here: Report update to this record