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Isolation of glycosidase-inhibiting hyacinthacines and related alkaloids from Scilla socialis.

Abstract:

An examination of the bulbs of Scilla socialis has resulted in the isolation of 11 hyacinthacines, two pyrrolidines, and three piperidines. The structures of the new alkaloids were elucidated by spectroscopic methods as beta-1-C-ethyldeoxymannojirimycin (5), hyacinthacines B7 (10), C2 (11), C3 (12), C4 (13), and C5 (14), and alpha-5-C-(3-hydroxybutyl)hyacinthacine A2 (15). Although, beta-l-homofuconojirimycin (3) and alpha-7-deoxyhomonojirimycin (alpha-7-deoxy-HNJ, 4) are previously known alk...

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Publication status:
Published

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Publisher copy:
10.1021/np0700826

Authors


Hollinshead, J More by this author
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Journal:
Journal of natural products
Volume:
70
Issue:
6
Pages:
993-997
Publication date:
2007-06-05
DOI:
EISSN:
1520-6025
ISSN:
0163-3864
URN:
uuid:41c1bca2-b37d-48a5-beba-0ba1708578f4
Source identifiers:
40363
Local pid:
pubs:40363

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