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Journal article

Proteomic analysis of membrane microdomains derived from both failing and non-failing human hearts.

Abstract:

Eukaryotic cells plasma membranes are organized into microdomains of specialized function such as lipid rafts and caveolae, with a specific lipid composition highly enriched in cholesterol and glycosphingolipids. In addition to their role in regulating signal transduction, multiple functions have been proposed, such as anchorage of receptors, trafficking of cholesterol, and regulation of permeability. However, an extensive understanding of their protein composition in human heart, both in fai...

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Publication status:
Published

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Publisher copy:
10.1002/pmic.200500278

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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Journal:
Proteomics
Volume:
6
Issue:
6
Pages:
1976-1988
Publication date:
2006-03-01
DOI:
EISSN:
1615-9861
ISSN:
1615-9853
Source identifiers:
229416

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