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Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo: relevance to endothelial dysfunction in hypercholesterolemia.

Abstract:

Flow-mediated dilatation (FMD) of conduit arteries is dependent on an intact endothelium, although the mechanisms are not fully understood. Using high-resolution ultrasound, we examined the role of endothelial mediators in radial artery dilatation in response to transient (short period of reactive hyperemia) and sustained (prolonged period of reactive hyperemia, hand warming, or an incremental infusion of acetylcholine into the distal radial artery) hyperemia. After short episodes of reactive...

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Publication status:
Published

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Publisher copy:
10.1161/01.res.88.2.145

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine
Role:
Author
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Journal:
Circulation research
Volume:
88
Issue:
2
Pages:
145-151
Publication date:
2001-02-05
DOI:
EISSN:
1524-4571
ISSN:
0009-7330
URN:
uuid:4188f103-0033-4bf5-9cbc-eb6089484226
Source identifiers:
105142
Local pid:
pubs:105142

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