Journal article
Duration of action of antispasmodic agents: novel use of a mouse model as an in vivo pharmacological assay.
- Abstract:
-
OBJECTIVE: Radial arteries are increasingly used as conduits for coronary artery bypass grafts, but perioperative graft vasospasm remains a concern. In vitro testing has demonstrated the efficacy of phenoxybenzamine and verapamil/nitroglycerin as topical antispasmodic agents, but their duration of action in vivo is unknown. Using an in vivo mouse model, we measured their duration of action in functioning vascular grafts, and compared this to their in vitro duration of action in ungrafted vas...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.ejcts.2004.06.018
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Bibliographic Details
- Journal:
- European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
- Volume:
- 26
- Issue:
- 5
- Pages:
- 988-994
- Publication date:
- 2004-11-01
- DOI:
- EISSN:
-
1873-734X
- ISSN:
-
1010-7940
- Source identifiers:
-
104956
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:104956
- UUID:
-
uuid:417ce196-efbb-40c7-9181-c06aad08c219
- Local pid:
- pubs:104956
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2004
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