Journal article icon

Journal article

Catechol-o-methyltransferase (COMT) and proline dehydrogenase (PRODH) mRNAs in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and major depression.

Abstract:

Catechol-o-methyltransferase (COMT) and proline dehydrogenase (PRODH) may both be susceptibility genes for schizophrenia. As part of the evaluation of their roles in psychosis, we used reverse transcription-polymerase chain reaction to measure COMT and PRODH mRNAs in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, major depression, and normal controls (n = 15 subjects in each group). We also genotyped two common COMT polymorphisms (-287A/G and 158Val/Met) which might af...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1002/syn.10286

Authors


Tunbridge, E More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Journal:
Synapse (New York, N.Y.)
Volume:
51
Issue:
2
Pages:
112-118
Publication date:
2004-02-05
DOI:
EISSN:
1098-2396
ISSN:
0887-4476
URN:
uuid:416f5bc0-7735-4ff0-b2eb-ab6d5194ebb8
Source identifiers:
97963
Local pid:
pubs:97963

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP